Wayne State University · Biomedical Engineering

Engineering ultrasound for quantitative imaging and precision therapy.

The TURE Laboratory develops next-generation ultrasound technologies that connect quantitative measurement with image-guided therapeutic intervention.

Ultrasound Tomography Theranostic Ultrasound Photoacoustic Imaging
Ring-array ultrasound and focused acoustic field visualization A stylized circular transducer array surrounds a quantitative imaging target with a focused acoustic field.
Quantitative imagingSpeed of sound · attenuation
Spatially controlled therapyImage-guided acoustic focusing

Our Mission

Measure more. Target precisely. Treat intelligently.

We integrate ultrasound tomography, photoacoustic imaging, therapeutic ultrasound, computational methods, and ultrasound-responsive drug carriers to create technologies that can characterize disease, guide treatment, and assess therapeutic response.

Our goal is to transform ultrasound from an imaging tool into an integrated platform for quantitative diagnosis and precision therapy.

Research

From quantitative imaging to image-guided therapy.

Our work spans technology development, computation, biological validation, and translation toward clinically meaningful applications.

01

Quantitative Ultrasound Tomography

We develop tomographic methods that characterize tissue using acoustic properties such as speed of sound and attenuation, while advancing reconstruction, acquisition, and computational imaging.

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03

Multimodal Biomedical Imaging

We integrate ultrasound with photoacoustic, elasticity, and molecular imaging to capture complementary anatomical, functional, and compositional information.

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Replace with your research figure
Recommended: ring-array system + quantitative image + acoustic field

Featured Platform

Quantitative ultrasound-guided precision therapy

Our research is developing ultrasound tomography as an integrated imaging and therapeutic platform. A programmable ring-array transducer can provide quantitative information for target identification and treatment planning while enabling spatially controlled acoustic energy delivery.

By accounting for tissue acoustic properties and shaping the transmitted field, we aim to localize therapeutic effects within complex targets while reducing exposure to surrounding tissue.

  • Quantitative tissue characterization
  • Image-guided acoustic field shaping
  • Ultrasound-triggered drug delivery
  • Therapy monitoring and feedback
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Applications

Engineering technologies around clinical questions.

Oncology

Precision Oncology

Quantitative ultrasound, targeted drug delivery, therapeutic ultrasound, and multimodal imaging for solid-tumor diagnosis, treatment planning, and response assessment.

Women's Health

Maternal-Fetal Health

Multimodal ultrasound, photoacoustic, and elasticity imaging for cervical remodeling, placental assessment, and maternal-fetal health.

Frontiers

Emerging Applications

Computational and point-of-care imaging technologies for neurological imaging, tissue characterization, and other challenging diagnostic applications.

People

People behind the research.

The TURE Laboratory brings together researchers interested in biomedical imaging, acoustics, computation, nanomedicine, and translational engineering.

Meet & join the team

Principal Investigator

Yan Yan, Ph.D.

Assistant Professor
Biomedical Engineering
Wayne State University

yyan2@wayne.edu

Highlights

Research, recognition, and lab news.

Research Highlight

Advancing ultrasound tomography-guided precision therapy

Developing quantitative ultrasound technologies that connect imaging, treatment planning, and spatially controlled therapeutic ultrasound.

Award · 2025

Best Paper Award at SPIE Medical Imaging

Recognition of research advancing biomedical ultrasound imaging and tomography.

Laboratory

Building the TURE Laboratory at Wayne State University

An interdisciplinary research program focused on quantitative biomedical imaging and image-guided therapy.

Opportunities

Join the TURE Laboratory.

We welcome motivated students and researchers interested in biomedical imaging, ultrasound tomography, therapeutic ultrasound, photoacoustic imaging, signal and image processing, nanomedicine, and AI-enabled biomedical technologies.