Wayne State University Department of Biomedical Engineering

Theranostic Ultrasound Research & Engineering

TURE Laboratory

We create quantitative ultrasound technologies that enable advanced diagnosis and precise image-guided therapeutic intervention.

Our Mission

Advancing quantitative ultrasound compute tomography (qUST) from imaging to integrated theranostics.

The TURE Laboratory aims to transform UST from a quantitative imaging technology into an integrated theranostic platform that supports tissue characterization, treatment planning, targeted therapeutic delivery, and treatment monitoring. By combining quantitative ultrasound imaging with therapeutic ultrasound, we seek to enable noninvasive, image-guided interventions in which diagnosis and therapy are performed within the same technological framework.

Yan Yan, Ph.D.

Principal Investigator

Yan Yan, Ph.D.

Assistant Professor
Department of Biomedical Engineering
Wayne State University

Dr. Yan leads the TURE Laboratory, developing quantitative ultrasound technologies that integrate advanced imaging with image-guided therapeutic intervention. His research focuses on advancing ultrasound computed tomography and therapeutic ultrasound toward integrated theranostic platforms for neurological disease and cancer.

Learn more about the TURE team →
Transcranial quantitative ultrasound tomography and image-guided brain therapy

Transcranial qUST & Image-Guided Brain Therapy

Developing quantitative transcranial ultrasound imaging and therapy guidance, including focused-ultrasound blood-brain barrier opening and related neurological applications.

Quantitative ultrasound tomography-guided precision cancer therapy

qUST-Guided Precision Cancer Therapy

Developing spatially controlled therapeutic platforms for rapid drug testing, ultrasound-responsive nanodroplets, and nanodroplet-assisted histotripsy.